Cleanroom ΔP & Air Quality Monitoring (GMP & Contamination Control)

GMP compliance

Differential Pressure (ΔP)

Temperature

Quick Overview

Problem

Cleanrooms and controlled environments in pharmaceutical, fine chemical, and high-purity process industries rely on precise pressure differentials and air quality control. Loss of differential pressure (ΔP) or airflow imbalance can lead to contamination, batch rejection, regulatory non-compliance, and costly downtime—often without immediate visibility.

Solution

Sensa.io’s wireless differential pressure and temperature sensors provide continuous monitoring of cleanroom pressure cascades and ventilation performance, ensuring GMP compliance and contamination control.

Value

GMP compliance • Reduced contamination risk • Lower audit effort • Stable production

ATEX

Generally non-ATEX; ATEX-certified sensor variants available when installed in solvent handling or classified zones

The Operational Challenge

Cleanrooms are used in chemical and process industries for:

  • Pharmaceutical synthesis and formulation
  • Fine chemicals and specialty materials
  • High-purity packaging and filling
  • Controlled laboratory and pilot environments

They depend on:

  • Stable pressure differentials between zones
  • Controlled airflow direction and volume
  • Reliable HVAC and filtration performance

Typical challenges include:

  • Loss of pressure cascade due to filter clogging
  • Fan degradation or damper malfunction
  • Undetected airflow imbalance between rooms
  • Manual checks too infrequent for continuous assurance

Traditional monitoring often involves:

  • Local manometers or gauges
  • Periodic manual readings
  • Reactive investigation after alarms or deviations

This leaves significant blind spots between inspections.

Why ΔP & Air Quality Monitoring Matter

Differential pressure is the primary indicator of cleanroom integrity.

Continuous monitoring enables operators to:

  • Maintain correct pressure cascades between zones
  • Detect filter clogging and ventilation issues early
  • Prevent contamination ingress or cross-contamination
  • Provide continuous proof of GMP compliance

Temperature data further supports HVAC performance analysis and comfort control.

Sensa.io Solution

Sensa.io delivers a wireless cleanroom monitoring solution for ΔP and air quality assurance.

Core Components

Differential Pressure Sensor

High-resolution ΔP measurement between cleanroom zones, corridors, and airlocks.

Temperature Sensor

Monitors HVAC performance and supports thermal stability requirements.

Wireless Communication

Supports LoRaWAN, Modbus, and MQTT, enabling integration with BMS, SCADA, and quality systems.

Installation & Power

Battery-powered installation — no cabling, no disruption to validated environments.

Operational Benefits

  • Continuous GMP compliance assurance
  • Reduced contamination risk
  • Faster deviation detection and response
  • Simplified audit and validation processes

Results and ROI

Metric Before After
Pressure cascade visibility Intermittent Continuous
Contamination risk Higher Reduced
Audit preparation effort High Reduced
Production stability Variable Stable

ATEX Compliance and Safety

When required, Sensa.io sensors support:

  • ATEX Directive 2014/34/EU
  • Ex II 2 G Ex ia IIC T4 Gb (Zones 0–2)
  • IECEx certification

This enables safe deployment in cleanrooms connected to solvent or flammable processes.

Integration and compatibility

Protocols

LoRaWAN, Modbus RTU/TCP, MQTT, REST API

Systems

BMS, SCADA, GMP quality systems

Vendors

Siemens, Schneider Electric, Honeywell, Johnson Controls

Cybersecurity

AES-128 encrypted communication

FAQ - Common Questions

Are Sensa.io sensors compatible with any gateway or network?

Yes, they connect to any LoRaWAN or MQTT infrastructure (Kerlink, Cisco, Milesight, MultiTech, etc.) for flexible integration with existing SCADA systems.

What ATEX certifications apply to Sensa.io devices?

All hazardous-area models are certified Ex II 2 G Ex ia IIC T4 Gb and IECEx approved for Zones 0–2.

What is the typical battery life?

Up to 10 years at 15-minute intervals, depending on signal strength and environment.

How are the sensors integrated into existing systems?

Through standard protocols — LoRaWAN, Modbus, MQTT, REST API — no proprietary middleware needed.

How does predictive maintenance reduce OPEX?

Early anomaly detection reduces emergency interventions by 30–40 %, extends equipment life and lowers energy costs.

What does the Sensa.io Valve Position Sensor actually measure?

The device detects real-time valve position states—open, closed, or intermediate—with high accuracy. It continuously sends this information wirelessly to your monitoring dashboard.

Can this sensor detect partial valve movement or stuck valves?

Yes. The sensor identifies irregular patterns such as partial movement, delayed response, or stuck valves, enabling early maintenance before failure occurs.

Is this sensor suitable for manual, motorized, and actuated valves?

Yes. It supports a wide range of valve types including ball, gate, butterfly, actuator-driven, and manual valves.

How fast does it update the valve position?

You can configure the reporting interval—from seconds to minutes—depending on your operational and battery needs.

How long does installation take?

Most installations take under 10 minutes. The sensor mounts using brackets or clamps without modifying existing valves.

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